An algorithm that can implement particle shape recognition and size measurement in hybrid particle field is proposed. Based on the defocused images obtained by the interferometric particle imaging (IPI) system, shape recognition of particles can be realized through ResNet50. Two-dimensional (2D) Fourier transform and 2D autocorrelation transform are used to obtain the size of spherical and non-spherical particles, respectively. The shape and size of the particle in hybrid particle field are determined. Numerical simulation and experiment results suggest that the method has good accuracy in measuring the particle size in hybrid particle field.